Wireless Electrical and Electromagnetic Pollution News
21 May 2010
May 20, 2010. The recent article, "Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case-control study" that appeared in the International Journal of Epidemiology on March 18, 2010, (2010:1-20) clearly demonstrates the flaws with the way wefund, conduct, review and report on science that deals with products that fetch billions of dollars and place at risk, at least potentially,billions of lives.
The INTERPHONE study, the largest (5,117 brain tumor cases) and most expensive ($25 million dollars) study on cell phones and brain tumors, involving scientists from 13 countries, was flawed from the very beginning. Whoever designed the protocol did it in such a way as to minimize finding any adverse effects. Despite this, adverse effects were reported — a 40% increased risk of glioma (a type of brain tumor that affects the glial cells in the brain) for those who used a cell phone for at least 1,640 hours with the highest risk for tumors in the temporal lobe and on the same side of the head that one exposes to the cell phone. In other words most of the tumors occurred in the part of the brain receiving the greatest radiation for those who had the longest exposure. And what did the authors do with this result? They attributed it to biases and error. Why?
Study design to minimize finding adverse effects of cell phones
First example: A regular cell phone user was defined as anyone who madeat least one call on their cell phone each week for at least 6 months! Would you expect a person to develop lung cancer if s/he smoked at least one cigarette a week for at least 6 months? By setting the number of calls so low (at least 24 calls on a cell phone) it dilutes the effect and favors a "no-effect" result.
Second Example: People who use cordless phones are exposed to virtually the same type of radiation yet they were not identified as exposed in this study. The cigarette analogy is comparing those who smoked one brand of cigarettes with those who smoked a different brand but this second group is labelled as "non-smokers". This also favors a "no-effect" result. We must recognize that even those people who do not use mobile phones (cell and cordless phones) are exposed to the radiation from nearby users, from nearby cell phone antennas and now from wireless routers as well as city-wide WiFi in a growing number of communities. So the best we can do is compare users with those who are exposed to the equivalent of second-hand smoke. This also under estimate the real risk of microwave exposure.
These two biases were so powerful that the final result showed that cell phones prevented brain tumors!
Third example: brain tumors take decades to develop in adults yet only a small fraction (less than 10%) of those people in this study used cell phones for more than 10 years. Just as you wouldn't expect to find lung cancer in a smoker after 4 to 5 years, you would not expect to find a brain tumor for a cell phone user during this short period of exposure either.
Forth example: participants were restricted to those between the ages of 30 to 59. Younger and more vulnerable participants were excluded from this study. This flaw is now being addressed with a new study based on younger users.
These experimental flaws and the obvious bias in the experimental design should have been caught early and corrected. But it wasn't. Why?
How could so many of the leading scientists in this field allow this to happen? Were they lured by the funding, which came-in part-from the very industry whose product was being studied? There were so many flaws in the experimental design that this article in the International Journal of Epidemiology should not have been accepted for publication by a peer-reviewed journal. Indeed, the reviewers, whoever they were, should have recommended that this article be rejected or accepted only after major revisions. This demonstrates problems with our peer-review process that the scientific community values so highly but that process is deeply flawed, and this is just one example.
This study demonstrates that funding (25% of which was provided by the wireless industry) can have a effect on the outcome of a publication. This has been shown time and again (with microwave radiation and with other environmental toxins including cigarettes) so why would we expect this study to be different. Indeed several of the authors identified conflicts of interest and associations with the wireless industry that went beyond the funding of this study.
It shows that a flawed experimental design produces unreliable results. The two major results from the Interphone study is that short-term use of cell phones provides protection against brain tumors and long-term use increases the risk of gliomas. The authors attributed both of these findings to biases and error!
Why were Appendix 1 and 2 published separately in the same journal? Why were these appendices not part of the original report? Was it because they showed higher levels of risk for both types of brain tumors?
Appendix 1 Interphone: While the original INTERPHONE study stated there was a decreased risk of meningiomas or no effect with cell phone use, Appendix 1 showed an 84% increase risk of meningiomas for those who used a digital phone for 1640 hours or more and those who used both digital and analogue cell phones or if type of phone used was unknown had a 343% increased risk or meningiomas!
Appendix 2 Interphone: In an attempt to try to "correct" the "downward bias" a mini report entitled Appendix 2 was published as a separate document in the same journal. This appendix compares regular users who used cell phones for less than 2 years (as the reference population) with those who used cell phones for longer periods.
The table in Appendix 2 provides some disturbing results. It shows that there is a statistically significant increased risk (68%) of developing gliomas for those who used a cell phone for as little as 2-4 years and 118%increased risk for those who used a cell phone for 10+ years. In the original study these exposure categories were shown to reduce risk of gliomas! See the highlighted areas in this table with comments. Indeed the 40%increased risk of glioma mentioned in the original study for those who used a cell phone for 1640 hours or more becomes an 82% increase when compared with regular cell phone users.
So what can we learn from this experience?
We learn that funding can influence the results of a study no matter how much scientists attempt to be objective.
We learn that bigger is not necessarily better. Had the $25 million dollars been given to independent scientists in various disciplines to determine the biological effects of cell phone use we would have been much further ahead than with the INTERPHONE study.
We learn that a flawed experimental design produces unreliable results. Even the authors of this study claim it is inconclusive and unreliable (since they state that the effects of due to biases and error).
We learn that compromise is necessary for setting standards and establishing policy but not for conducting science. Science is not done by committee or by consensus and compromise. The majority is not always right and we have plenty of examples from various scientific disciplines to demonstrate this.
As I read the INTERPHONE report and interviews with participating scientists I sensed the frustration with the process and can now understand why it has taken so long to produce this document. I expect that some of those involved are deeply frustrated and perhaps even embarrassed by the outcome.
Elizabeth Cardis, head of the INTERPHONE study, was quoted as stating: "Until stronger conclusions can be drawn one way or another it may be reasonable to reduce one's exposure." This is a wise comment that we should all heed.
Cardis is a co-author of a paper showing an increase in Salivary Gland Tumoron the same side of the head that one exposes to a cell phone after a 10-year latency period. She is also now heading up a study with young users, called Mobi-Kids. Let's hope that this new study corrects the flaws of the INTERPHONE study and produces reliable results.
Major advances in science often start with individuals who are curious and want to come as close as possible to understanding the truth about some aspect of our physical reality; individuals who are able to put aside their preconceived notions when they stumble across an unexpected result. Indeed it is these unexpected results that propel our understanding of science and it is those who recognize the value of the unexpected who become known for their "discoveries".
Thomas Kuhn described this process and called it a paradigm shift. It refers to a revolutionary change in the way we understand some aspect of science. It is often opposed until the evidence becomes so overwhelming that it can no longer be denied.
We are currently in the midst of a paradigm shift when it comes to understanding the biological effects of non-ionizing radiation. The evidence that this form of energy causes biological and health effects that are unrelated to heating is now overwhelming. It won't be long before the "old school" of thinking is replaced with the new, and when this happens we will see rapid growth in our understanding of both the harmful and healing effects of this type of radiation. It is my hope that we will also see a shift to safer technology and improved guidelines for protecting public health.
To ensure this happens within the next decade rather than the next century we need independent funding of science on the biological effects of non-ionizing electromagnetic energy. The money spent on research will be repaid many times with the money saved on health care costs, disability compensation for those who develop electrohypersensitvitiy, and improved performance at work and school.
Dr. Magda Havas, B.Sc., Ph.D.,
Environmental & Resource Studies, Trent University, Peterborough, ON, Canada, K9J 7B8
phone: 705 748-1011 ext 7882
fax: 705 748-1569
email: drmagdahavas@gmail.com
Critics hit at 'flawed' mobile phone cancer study
Published: May 18 2010 03:00
The largest-ever international study of mobile phone safety has concluded
the devices do not raise the risk of brain cancer - except possibly a slight
increase in tumours among the most intensive users.
The telecoms industry, which contributed $6m (€5m, £4m) to the $24m
Interphone study through an "arm's length" funding mechanism, said the
findings, published yesterday, supported its view that mobile phones were
safe. But the industry said it was prepared to support more research.
Critics said the study used flawed methodology that concealed a more
worrying increase in glioma, the most deadly brain tumour, in the heaviest
mobile users - those who have used mobile phones for more than 1,640 hours.
WiredChild, a UK pressure group, said the implications for children - not
included in the Interphone study - were serious.
Scientists in 13 countries carried out the study under the auspices of the
International Agency for Research on Cancer, part of the World Health
Organisation. They interviewed 5,100 brain cancer patients and a similar
number of matched "controls", who did not have cancer, about their mobile
phone use.
Although data collection ended in 2004, publication of the study was delayed
while the researchers argued about how best to present their results. It
eventually appeared yesterday in the International Journal of Epidemiology .
A particular issue was the finding that regular mobile users had less brain
cancer than non-users matched for sex, age and social background - though
there is no biologically plausible way phones could actually protect against
tumours.
When the results are adjusted to correct for this apparent flaw in the study
method, there is a larger increase in cancer risk among the most intense
mobile users.
"An increased risk of brain cancer is not established from the data from
Interphone," said Dr Christopher Wild, IARC director, summing up the study.
"However, observations at the highest level of cumulative call time and
changing patterns of mobile phone use since the period studied by
Interphone, particularly in young people, mean that further investigation of
mobile phone use and brain cancer risk is merited."
The leaders of the study in the UK, Professors Anthony Swerdlow of the
Institute of Cancer Research and Patricia McKinney of Leeds University, were
more dismissive of any apparent causal link between mobile phone use and
brain cancer.
Almost 4,000 residents object to proposed phone mast in east Hull
From left, campaign spokesman Tony Bakes, Cliff Brooks and Hull East MP Karl Turner are opposing plans for a mobile phone mast
The protest by residents living in the James Reckitt Avenue area is one of the largest seen in recent years over a single planning issue in the city.
Mobile phone firms O2 and Vodaphone want to install the new mast and two equipment cabins at the junction of James Reckitt Avenue and Gilshill Road, just yards from the entrance to East Park.
Recent ground work carried out at the site on behalf of the two companies has already angered residents.
Campaign spokesman Tony Bakes said: "The residents all feel very strongly over the negative effect this mast will have on the community, should it go ahead.
"There are many concerns, from the likely visual impact and pedestrian safety in relation to the siting of the equipment cabins to the potential for anti-social behaviour and a drop in property prices.
"Within the area directly targeted by the microwaves from this mast are four schools - Malet Lambert Language College, Gillshill Primary School, Cavendish Primary School and Westcott Primary School."
New Hull East MP Karl Turner is backing the residents' fight.
He said: "Clearly everyone likes using mobile phones but I believe this is not the best location for a mast like this.
"The residents have got some very genuine concerns and I will be doing my best to look at whether it is possible to introduce legislation which gets councils to identify potential sites for these sort of masts instead of having companies rolling up on peoples' doorsteps."
A Vodaphone spokesman said the ground works had been carried out on a trial basis.
Under planning law, most mobile phone masts are automatically regarded as permitted development as long as they are under 15 metres high and the equipment cabins fall within permitted volume levels.
However, firms have to give notice to the relevant local council before starting construction work, allowing the authority to decide whether it wishes to grant planning approval for the siting or appearance of the mast.
The council's planning committee is expected to decide on the issue later this summer.
Submitted by Robert
