Monday, February 1, 2010

Ban it! / Fertility Warning

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1: Fertil Steril. 2007 May 3; [Epub ahead of print] Related Articles, Links
Click here to read 
Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study.

Agarwal A, Deepinder F, Sharma RK, Ranga G, Li J.

Reproductive Research Center, Glickman Urological Institute and Department of Obstetrics-Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio.

OBJECTIVE: To investigate the effect of cell phone use on various markers of semen quality. DESIGN: Observational study. SETTING: Infertility clinic. PATIENT(S): Three hundred sixty-one men undergoing infertility evaluation were divided into four groups according to their active cell phone use: group A: no use; group B: <2 h/day; group C: 2-4 h/day; and group D: >4 h/day. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Sperm parameters (volume, liquefaction time, pH, viscosity, sperm count, motility, viability, and morphology). RESULT(S): The comparisons of mean sperm count, motility, viability, and normal morphology among four different cell phone user groups were statistically significant. Mean sperm motility, viability, and normal morphology were significantly different in cell phone user groups within two sperm count groups. The laboratory values of the above four sperm parameters decreased in all four cell phone user groups as the duration of daily exposure to cell phones increased. CONCLUSION(S): Use of cell phones decrease the semen quality in men by decreasing the sperm count, motility, viability, and normal morphology. The decrease in sperm parameters was dependent on the duration of daily exposure to cell phones and independent of the initial semen quality.

PMID: 17482179 [PubMed - as supplied by publisher]

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Ban it!

Posted by: Nadhiya Mali on: February 1, 2010


Ban it

http://nadhiscorner.wordpress.com/2010/02/01/ban-it/#comment-167

Deepa is my neighbor, a good friend and a 27 year old expecting mother.  She conceived after four years of her blissful married life. The couple is perhaps the happiest couple; strong and confident, solved every hurdle they could before settling down for a baby. She quit her job the next day after she got her pregnancy report.

18th August 2009:

Deepa was three months pregnant. She could not wait to be a mom

12th November 2009:

Doctor says baby is very healthy and marks the due date on 15th of March 2010. Deepa leaves to her Mom's place for a safe delivery. Her parents live in Kanchipuram

28thJanuary 2010:

Deepa is in to her eighth month. Doctor in Kanchipuram says there is a problem with the baby and orders them to leave to Chennai immediately and take a 3D Scan

29th January 2010:

Deepa comes to Chennai and explains the problem to her doctor. The scan is taken and the doctor does not feel sorry that the problem has not been rectified earlier.

31st January:

Deepa is admitted to the hospital immediately and is injected Oxytocin(to induce labor pain).

1st February 2010:

Deepa has a forced labor and the baby dies within two hours

Now what was the actual problem?  The baby's brain and the nervous system failed to develop to its full extent.

Reason: The doctor cited Heavy Mobile phone usage as a reason. Apparently Deepa didn't have a landline phone at her in-laws and used only her mobile, whenever she had to make a call

Let's not debate on whether a Mobile phone is safe to use during pregnancy.

If you know someone who is pregnant ask her to follow these simple measures:

  1. Minimize the use of mobile phone
  2. Text a person instead of making a call
  3. Use landline.
  4. Always keep the phone at a distance
  5. Never take a call when the charge on your phone is low
  6. Switch off the phone when you go to bed at night. If you have to keep an alarm, there is an alarm clock invented for the purpose

Pregnancy is the most beautiful part of a women's life. Don't take risks

TAKE CARE

--------------------------

Note - There are some interesting comments after the article.  They can be read at  - http://nadhiscorner.wordpress.com/2010/02/01/ban-it/#comment-167 

There is an important article below, by Dr. Andrew Goldsworthy

Please also see the attached documents on how EMR affects fertility.

Martin Weatherall

www.weepinitiative.org

--------------------------------------------------------------------------------------------------------------------------------------------

 
 
 
Fertility Warning
 
 

Most of the "modern illnesses" that have arisen since our dramatic increase in exposure to non-ionizing electromagnetic radiation can be plausibly linked to the weakening of cell membranes by the release of structurally-important calcium ions (see http://tinyurl.com/5ru6e6 for details, including the mechanism).

 

Almost certainly, the most important are the effects on fertility and genetic damage in the germ line [The germ line contains all those cells that transmit genetic information from one generation to the next. They include not only the eggs and sperm, but also the line of body cells from the embryo onwards that lead to their production. For example, the cells that divide to give rise to the sperm are in the germ line, but those of an arm or a leg are not]. There have been several papers now linking mobile phone radiation to DNA damage in human cell cultures and a consequent loss of male fertility. A recent one by Agarwal et al. in Cleveland, Ohio (Fertility and Sterility. Vol. 89. pp 124–128. 2008) showed that men using mobile phones for more than 4 hours a day lost over a third of their sperm count and over half of what were left showed physical abnormalities, did not swim well or were non-viable (see attachment for an online version). There could be still more with genetic defects that do not show up under the microscope, but will appear as mutations and deformities in future generations.

 

Gametes, such as eggs and sperm are particularly sensitive to genetic damage since they are haploid, so double stranded DNA breaks cannot be repaired by the normal mechanism used in diploid cells. In diploid cells, the damaged section is excised and replaced by a copy of the corresponding section of the homologous chromosome (Mechanism of Eukaryotic Homologous Recombination .Filippo, Sung and Klein. Annu. Rev. Biochem. Vol 77 pp 229–57. 2008. 77). This sort of replacement is not possible in the haploid gametes, so the damage may remain unrepaired and accumulates.

 

Effects of mobile phone use on female fertility have not been studied but, since all the eggs that a woman will ever have were in her ovaries before she was born, there could be even greater cumulative damage. To make a sperm from scratch takes about three months. If eggs were to be damaged at a similar rate to sperm, we might expect many women making heavy use of mobile phones to be virtually sterile by the time they want to conceive. Wi-Fi laptops (which use a similar technology) could present an even greater fertility and genetic hazard since they are used closer to the gonads and compulsory exposure to their radiation for several hours a day is now the norm in many schools.  Increased attendance at IVF clinics and cost to the NHS is to be anticipated.

 

The mechanism by which this damage is being caused is now becoming clear. There have been several papers linking short term exposure of semen to sperm damage and the production of reactive oxygen species (possibly as a result of mitochondrial membrane damage), which can cause the fragmentation of DNA (see

http://www.renalandurologynews.com/Cell-Phone-Use-Could-Damage-Semen/article/157370/ ).

 

This can be turned to advantage since these experiments can have exactly matched controls and require only brief exposures of donated sperm to give results, possibly within the day. They could be used as pre-market tests for the biological safety of new wireless technologies before they are rolled out and also for testing modifications to existing technologies to make them safer.  Such modifications are possible and, if they live up to expectations, could transform the harmful effects of the radiation into net beneficial effects. That can't be bad can it?

 

Best wishes

 

Andrew

 

(Dr. Andrew Goldsworthy)